Bioavailability and its assessment. - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Accéder directement au contenu
Article Dans Une Revue Journal of Veterinary Pharmacology and Therapeutics Année : 2004

Bioavailability and its assessment.

Résumé

Bioavailability is a key pharmacokinetic parameter which expresses the proportion of a drug administered by any nonvascular route that gains access to the systemic circulation. Presented in this review are the different approaches to measurement of bioavailability (absolute and relative), including the case in which intravenous administration is impossible. The rate of drug absorption is also discussed with special emphasis on the possible difficulties encountered using C(max) and T(max) or curve fitting to evaluate the rate of drug absorption.

Domaines

Pharmacologie

Dates et versions

hal-00517568 , version 1 (14-09-2010)

Identifiants

Citer

Pierre-Louis Toutain, Alain Bousquet‐mélou. Bioavailability and its assessment.. Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (6), pp.455-66. ⟨10.1111/j.1365-2885.2004.00604.x⟩. ⟨hal-00517568⟩
63 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More