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Article Dans Une Revue Food and Function Année : 2015

Intestinal absorption of vitamin D: from the meal to the enterocyte

Résumé

Vitamin D plays key roles in bone, infectious, inflammatory and metabolic diseases. As most people get inadequate sun exposure for sufficient vitamin D status, they need adequate intake of dietary vitamin D. Many studies see optimizing vitamin D status as a public health priority. It is thus vital to gain deeper insight into vitamin D intestinal absorption. It was long assumed that vitamin D intestinal absorption is a passive process, but new data from our laboratory showed that it is actually far more complex than previously thought. This review describes the fate of vitamin D in the human upper gastrointestinal lumen during digestion and focuses on the proteins involved in the intestinal membrane and cellular transport of vitamin D across the enterocyte. Although recent data significantly improve our understanding of vitamin D intestinal absorption, further studies are still needed to increase our knowledge of the molecular mechanisms underlying this phenomenon
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Dates et versions

inserm-01478584 , version 1 (28-02-2017)

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Emmanuelle Reboul. Intestinal absorption of vitamin D: from the meal to the enterocyte. Food and Function, 2015, 6 (2), pp.356 - 362. ⟨10.1039/c4fo00579a⟩. ⟨inserm-01478584⟩
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