Lettuce mosaic potyvirus (LMV) has been a destructive virus on lettuce crops and the emergence of new strains requires to find out new resistance genes. The coat protein mediated protection approach was shown previously to confer some protection to LMV. Additional transformed lettuce lines were analysed for resistance against LMV-0. The R2 homozygous progenies of four R1 resistant Jessy plants showed a protection against LMV similar to the one obtained in the R2 Cocarde line (Cocarde 9a-91) initially described. Only few plants showed a complete resistance and a large majority of R2 plants of each progeny showed a recovery phenotype. This LMV protection phenotype was transmitted after cross with untransformed lettuce. A new screening of transgenic lettuce plants was performed on R1 plants and did not allow the characterization of highly resistant plants. Therefore, the protection conferred by the LMV-0 coat protein seems to be triggered only after a period 5 to 7 weeks after inoculation, period during which plants can not develop any resistance to virus infection.